Deion Sanders’ team is, unsurprisingly, the talk of college football once again heading into a Week 2 showdown with Nebraska.

Everyone appears to be aboard the Colorado hype train as it runs away from the station. But they could very well lose this Saturday’s matchup with Nebraska—even at home.

On today’s episode of Locked On Pac-12, I talk about the biggest matchup in the league—and perhaps all of college football—taking place Saturday morning in Boulder.

Plus, I give a big key/question for every other Pac-12 game and his score predictions for Week 2’s loaded slate of games.

After going 4-1 last week, I bring back my Pac-12 Prime Picks with the best bets across the league in Week 2.

I like Nebraska and Cal to win outright as underdogs this week, but aside from that I’m riding several favorites heading into the weekend.

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—More from Spencer McLaughlin—

• McLaughlin: Can Conference Relegation Save the Pac-2?

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• McLaughlin: Utah Needs Cam Rising to Return to Win Pac-12

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• McLaughlin: OSU vs. WSU Set to Make a Point on Saturday

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• McLaughlin: Pac-12 Moods, Week 3 Winners and Losers

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• McLaughlin: Week 3 Shows CFB has Scheduling Problem

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• McLaughlin: What Do We Know About These 2023 Beavers?

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• McLaughlin: Is Colorado a Serious Pac-12 Title Contender?

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• McLaughlin: OSU and WSU Seek to Control their Futures

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• McLaughlin: Pac-12 Showing Why Demise is Totally Insane

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• McLaughlin: Pac-12 Remains Best Conference in America

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• McLaughlin: Why Utah Should be Pac-12 Favorite, but Isn’t

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• McLaughlin: Colorado Could Start 3-0 After Upset of TCU

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• McLaughlin: The Pac-12’s Path to the CFP Remains Daunting

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• McLaughlin: Reaction to Cal and Stanford Going to the ACC

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• McLaughlin: Pac-12/Mtn West ‘Reverse Merger’ Plausible?

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