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McLaughlin: Can Hoosiers Spoil Oregon’s Home Win Streak?

> Spencer discusses Indiana's quest for the biggest win in its football program's history
, 1 min read
Indiana QB Fernando Mendoza and Oregon QB Dante Moore
Spencer McLaughlin talks about what Indiana needs to do to shock the Ducks in Autzen on Saturday | Jeffrey Becker, Troy Wayrynen / Imagn Images


  By Spencer McLaughlin of Locked on CFB for SuperWest Sports

October 10, 2025


Big Ten logo

Indiana travels to Oregon this weekend looking for the biggest win for its program of all time.

How can the Hoosiers upset Dan Lanning’s Ducks in Eugene?

On today’s episode of Locked On College Football, Spencer McLaughlin makes his picks for all the big games of the week.

usc logoWill Michigan falter at USC? Will Bama stumble at Missouri? Will BYU suffer its first loss?

Spencer concludes the show with his best bets for the week in desperate need of getting over .500 for a slate of games.

FanDuel.com is the place to go if you wish to fade his picks–starting with Texas A&M beating Florida handily.

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