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McLaughlin: Key Games and Best Bets for Week 3 in CFB

> Spencer gives us his picks for a selection of contests with potential Playoff implications


  By Spencer McLaughlin of Locked on CFB for SuperWest Sports

September 12, 2025



SEC logoNotre Dame’s Playoff hopes are on the line this week against Texas A&M, the Irish simply cannot afford a loss.

Alabama needs to look good against Wisconsin.

On today’s episode of Locked On College Football, I discuss a Playoff-implicated game when Duke travels to Tulane.

The Green Wave have a MASSIVE opportunity against the Blue Devils on their home field in a return trip for QB Darian Mensah.

USF espnI conclude today’s show by talking about his best bets for the week in College Football.

Can South Florida hang with Miami? Will West Virginia keep it tight with Pitt in the Backyard Brawl?

0:00 Notre Dame’s margin for error
5:06 Clemson’s offensive struggles against Georgia Tech
13:43 Duke vs Tulane: Potential G5 playoff implications
15:45 Alabama needs dominant win over Wisconsin
21:53 Best bets for Week 3 college football
28:30 Oregon heavily favored against Northwestern

   / @lockedoncollegefootball  

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