How will Arizona respond to a massive win in Week One? How will USC look against a Power 5 opponent in Stanford? Will Oregon State’s defense replicate its stellar performance in a road showdown with Fresno State?

These are just some of the questions Pac-12 football fans will look to have answered as the second weekend of games approaches.

On today’s episode of Locked On Pac-12, I get ready for the upcoming slate of games the Pac-12 has in front of it.

The three biggest games for the Conference this weekend involve Oregon State, Arizona, and the first in-conference matchup featuring Stanford and USC.

I lay out the most important facets of each game that will ultimately decide the outcome.

CBS College Football Analyst Danny Kanell joins the show to look at the upcoming weekend of betting in the Pac-12 for my weekly “Pac-12 Prime Picks” (which weren’t so prime in Week One).

Arizona State has a tough road matchup against Oklahoma State and is a heavy underdog, and may have a tough time covering 11 points on the road in Stillwater.

Oregon State has a tight line down in Fresno this weekend as -1.0 favorites, and both Danny and Spencer like the Beavers again this week.

Their point of difference comes on the Cal Bears, who are almost two-touchdown favorites against UNLV.

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—More from Spencer McLaughlin—

• McLaughlin: Is USC on Upset Alert against Oregon State?

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• McLaughlin: Oregon RBs, Potential Breakout Players at WSU

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• McLaughlin: UCLA’s ‘Slow’ Start, Biggest Week 4 Headlines

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• McLaughlin: Pac-12 Football Looks Strong Through 3 Weeks

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• McLaughlin: CFB Coaches Arizona State Should be Targeting

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• McLaughlin: Winners and Losers from a Big Pac-12 Weekend

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• McLaughlin: Important Week 3 Factors for USC, UW and Cal

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• McLaughlin: Arizona, ASU & WSU Should be on High Alert

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• McLaughlin: Huskies Have Biggest Opportunity in Week 3

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• McLaughlin: Can Lincoln Riley keep the Trojans Rolling?

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• McLaughlin: USC and WSU Win the Pac-12 Football Weekend

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• McLaughlin: Pac-12 Football Might be in for a Rough Week 2

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• McLaughlin: Pac-12 Winners and Losers from Week 1

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• McLaughlin: Are the Pac-12’s CFB Playoff Hopes Gone?

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• McLaughlin: Pac-12 Football Brand takes a Major Hit

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• McLaughlin: Pac-12 could Strengthen its Brand with Big Wins

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• McLaughlin: Is Colorado Being Undervalued this Season?

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• McLaughlin: What ASU and CU Could Show in Their Openers

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• McLaughlin: Pac-12 Coaches Who May Not Survive 2022

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• McLaughlin: The 5 Most Important Pac-12 QBs for 2022

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• McLaughlin: Preseason Pac-12 Football Recruiting Update

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• McLaughlin: What Penix Brings to Huskies as Starting QB

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• McLaughlin: Wins Hard to Find on 2022 Cal Schedule

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• McLaughlin: Why Cardinal will Bounce Back in 2022

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• McLaughlin: Oregon State Football Underrated in 2022

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• McLaughlin: How Ducks can flip script and beat Utah in 2022

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• McLaughlin: Oregon Football Poised for Success in 2022

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• McLaughlin: Can ASU Match its 2021 Win Total?

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• McLaughlin: Wildcats will Increase Win Total in 2022

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• McLaughlin: WSU Should be Over .500 Again in 2022

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